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Characterization and mapping of DNA damage induced by reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) at nucleotide resolution in human genomic DNA

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[176] The study suggested "that television increased the share of smokers in the population by 515 percentage points, generating roughly 11 million additional smokers between 1946 and 1970." [176] In the United States, a 2019 analysis by the Centers for Disease Control and Prevention of top-grossing films released during 20102018 found that, although the number of films with any tobacco imagery remained stable, the total number of tobacco incidents in those films increased by 57%, including a 120% increase in PG-13-rated movies